Entera Bio Provides Corporate Updates and Financial Results for the Third Quarter of 2022

JERUSALEM, Nov. 10, 2022 (GLOBE NEWSWIRE) — Entera Bio Ltd. (NASDAQ: ENTX), ("Entera" or the "Company") a leader in the development of orally delivered peptides and therapeutic proteins, today announced its financial results for the third quarter of 2022 and provided the following corporate updates.

Corporate Updates:

Achieved FDA Agreement for Pivotal Study of EB613, the World's First Daily Bone Forming Oral PTH Tablet

  • On October 6th, 2022, Entera announced that it had successfully completed its Type C meeting and reached a record agreement with the U.S. Food and Drug Administration (FDA) that a single pivotal Phase 3 placebo–controlled study could support a New Drug Application (NDA) submission for its lead clinical candidate, EB613 under the 505(b)(2) regulatory pathway.
  • Importantly, the FDA also agreed that total hip bone mineral density (BMD), not fracture, could serve as the primary endpoint for the registrational study of EB613; and that Entera could enroll the same post–menopausal osteoporosis patient population that significantly benefited from EB613 treatment during Entera's Phase 2 clinical study which was reported in 2021.
  • EB613 is the first oral, daily tablet formulation of synthetic hPTH (1–34), (teriparatide), consisting of the exact same 34 amino acid sequence as daily subcutaneous teriparatide injection, Forteo which has been the leading anabolic treatment of osteoporosis since 2002 with peak sales of $1.7 billion in 2018 prior to patent expiration. EB613 tablets are simple, small (~ 6 mm wide) and administered once daily.
  • Low BMD osteoporotic patients at high risk of fracture are often reluctant to initiate injectable anabolic (bone forming) therapy and represent an estimated 40% of the 3 million currently treated patients across the United States, while current bone forming injections treat less than 10% of these patients1. As the first daily tablet PTH osteoanabolic treatment, EB613 could significantly impact the osteoporosis treatment paradigm. Patient enrollment in the pivotal phase 3 study is expected to commence in 2023.

New Phase 2 Data Presented at the ASBMR Annual Meeting Demonstrate Statistically Significant Correlation of EB613's Dose Proportional Oral Absorption and Clinical Benefit

  • New findings on EB613 were presented in a poster titled "A Six–month Phase 2 Study of Oral PTH (EBP05) in Postmenopausal Women with Low Bone Mass "" Dose Proportional Absorption and Effect on Lumbar Spine BMD (SUN–591)" at the American Society for Bone and Mineral Research (ASBMR) 2022 Annual Meeting in September.
  • New analyses of hPTH concentration in blood shortly after a dose of EB613 tablets confirmed a strong, statistically significant correlation between mean blood level and the dose of EB613 taken.
  • These findings are consistent with the positive correlation between the change in lumbar spine BMD and EB613 dose after six months of treatment.

"Following a full redesign of our proposed Phase 3 study, timely submission, and successful conclusion of our Type C meeting, our third quarter culminated with the FDA's concurrence with our proposed registrational path for EB613. This was an historic moment for Entera. We believe this is the first osteoporosis program that has reached agreement on both a placebo–controlled design and a BMD endpoint, which we believe speaks to the urgent need for highly effective and more patient friendly treatments to help rebuild bone. EB613 leverages the validated and safe mechanism of action of PTH which has been at the forefront of osteoporosis therapy for the last 20 years, and addresses patients' unease with injections via our simple daily tablet form. We continue to strengthen all functional areas at Entera to remain on track for patient enrollment to commence in 2023, while continuing our strategic discussions and preparing our new formulation of EB612 PTH tablets for hypoparathyroidism to re–enter the clinic in 2023," stated Miranda Toledano, Chief Executive Officer of Entera.

Results for Third Quarter Ended September 30, 2022

Revenues for the three months ended September 30, 2022 were $8,000 compared to $140,000 for the three months ended September 30, 2021. For both the three months ended September 30, 2022 and 2021, the majority of our revenues were attributable to pre–clinical R&D services provided to Amgen as part of our ongoing license agreement. The decrease in revenue for the quarter ended September 30, 2022 as compared to the prior year period was primarily due to finalization of third year pre–clinical R&D services to Amgen. The cost of revenues for the three months ended September 30, 2022 was $6,000 compared to $65,000 for the three months ended September 30, 2021 and were primarily attributed to expenses in connection with R&D services provided to Amgen.

Research and development expenses for the three months ended September 30, 2022 were $1.4 million compared to $1.8 million for the three months ended September 30, 2021. The decrease of $0.4 million was primarily due to a decrease of $0.7 million in pre–clinical activities related to our Phase 3 clinical trial for EB613 and a decrease of $0.1 million related to the completion of our Phase 2 trial for EB613 in September 2021. This decrease was partially offset by an increase of $0.1 million in connection with a one–time employee compensation payment as part of a separation agreement and an increase of $0.3 million attributed to ongoing materials and production costs to supply our Phase 3 clinical trial for EB613.

General and administrative expenses for both the three months ended September 30, 2022 and 2021 were $1.5 million. For the quarter ended September 30, 2022, there was an increase of $0.2 million in professional fees and an increase of $0.1 million in D&O insurance costs, as compared to the 2021 period, which was offset by a decrease of $0.3 million in share–based compensation mainly due to a reversal of share–based compensation expense related to the separation agreement of our former Chief Executive Officer.

Operating expenses for the three months ended September 30, 2022 were $2.9 million compared to $3.3 million for the three months ended September 30, 2021. Entera's operating loss was $2.9 million for the three months ended September 30, 2022, compared to $3.2 million for the three months ended September 30, 2021.

The net comprehensive loss was $3.1 million or $0.11 per ordinary share (basic and diluted) for the three months ended September 30, 2022, compared to $3.2 million, or $0.11 per ordinary share (basic and diluted) for the three months ended September 31, 2021.

As of September 30, 2022, Entera had cash and cash equivalents of $14.3 million, compared to $17.3 million as of June 30, 2022. Entera expects that its existing cash resources are sufficient to fund operations through the second quarter of 2023. This assumes ongoing R&D, the Hypo PK study and continued investments in production, analytics, and clinical research operations to enable initiation of EB613 phase 3 during the second half of 2023.

About EB613 (a.k.a. EBP05)

EB613 is the first oral, daily tablet formulation of synthetic hPTH (1–34), (teriparatide), consisting of the exact same 34 amino acid sequence as daily subcutaneous teriparatide injection, Forteo which has been the leading anabolic treatment of osteoporosis since 2002 with peak sales of $1.7 billion in 2018 prior to patent expiration. Entera's Oral PTH formulations have been administered collectively to a total of 225 subjects in two Phase 1 studies and 3 phase 2 studies (including 35 in 2 phase 2 hypoparathyroidism studies). The most recent study was a dose ranging Phase 2 study in postmenopausal women with low bone mass. This study met primary and key secondary endpoints and was presented in a late–breaker oral presentation at the ASBMR 2021 conference. For the primary efficacy endpoint: a statistically significant increase in P1NP (a bone formation marker) at 3 months was achieved. A significant dose response was observed for 0.5, 1.0, 1.5 and 2.5 mg oral PTH doses on P1NP, Osteocalcin and bone mineral density (BMD). Subjects receiving the 2.5 mg dose of EB613 showed significant increases in dose–related BMD at the Lumbar Spine, Total Hip, and Femoral Neck at 6 months. Subjects receiving the 2.5 mg dose of EB613 daily for 6 months had a significant placebo adjusted increase of 3.78% in Lumbar Spine BMD (p<0.008) which is similar to the 3.9% increase in Lumbar Spine BMD seen with Forteo in clinical studies reported in the literature. Increases in Total Hip and Femoral Neck BMD were greater than those previously reported with Forteo at 6 months. EB613 exhibited an excellent safety profile, with no drug related serious adverse events. The most common adverse events included mild nausea, moderate back pain, moderate headache, and moderate upper abdominal pain.

About Entera Bio

Entera is a leader in the development of orally delivered macromolecules therapeutics including peptides and other therapeutic proteins, for use in areas with significant unmet medical need where adoption of injectable therapies is limited due to cost, convenience and compliance challenges for patients. The Company's proprietary, oral drug delivery technology is designed to address the technical challenges of poor absorption, high variability, and the inability to deliver large molecules to the targeted location in the body through the use of a synthetic absorption enhancer to facilitate the absorption of large molecules, and protease inhibitors to prevent enzymatic degradation and support delivery to targeted tissues. The Company's most advanced product candidates, EB613 for the treatment of osteoporosis and EB612 for the treatment of hypoparathyroidism are in clinical development. Entera also licenses its technology to biopharmaceutical companies for use with their proprietary compounds and, to date, has established a collaboration with Amgen Inc. For more information on Entera Bio, visit www.enterabio.com.

Contact:

Entera Bio:
Ms. Miranda Toledano
Chief Executive Officer
Entera Bio
Email: miranda@enterabio.com

Cautionary Statement Regarding Forward Looking Statements

Various statements in this press release are "forward–looking statements" within the meaning of the Private Securities Litigation Reform Act of 1995. All statements (other than statements of historical facts) in this press release regarding our prospects, plans, financial position, business strategy and expected financial and operational results may constitute forward–looking statements. Words such as, but not limited to, "anticipate," "believe," "can," "could," "expect," "estimate," "design," "goal," "intend," "may," "might," "objective," "plan," "predict," "project," "target," "likely," "should," "will," and "would," or the negative of these terms and similar expressions or words, identify forward–looking statements. Forward–looking statements are based upon current expectations that involve risks, changes in circumstances, assumptions and uncertainties. Forward–looking statements should not be read as a guarantee of future performance or results and may not be accurate indications of when such performance or results will be achieved.

Important factors that could cause actual results to differ materially from those reflected in Entera's forward–looking statements include, among others: changes in the interpretation of clinical data; results of our clinical trials; the FDA's interpretation and review of our results from and analysis of our clinical trials; unexpected changes in our ongoing and planned preclinical development and clinical trials, the timing of and our ability to make regulatory filings and obtain and maintain regulatory approvals for our product candidates; the potential disruption and delay of manufacturing supply chains; loss of available workforce resources, either by Entera or its collaboration and laboratory partners; impacts to research and development or clinical activities that Entera is contractually obligated to provide, such as those pursuant to Entera's agreement with Amgen; overall regulatory timelines; the size and growth of the potential markets for our product candidates; the scope, progress and costs of developing Entera's product candidates; Entera's reliance on third parties to conduct its clinical trials; Entera's expectations regarding licensing, business transactions and strategic collaborations; Entera's operation as a development stage company with limited operating history; Entera's ability to continue as a going concern absent access to sources of liquidity; Entera's ability to obtain and maintain regulatory approval for any of its product candidates; Entera's ability to comply with Nasdaq's minimum listing standards and other matters related to compliance with the requirements of being a public company in the United States; Entera's intellectual property position and its ability to protect its intellectual property; and other factors that are described in the "Cautionary Statements Regarding Forward–Looking Statements," "Risk Factors" and "Management's Discussion and Analysis of Financial Condition and Results of Operations" sections of Entera's most recent Annual Report on Form 10–K filed with the SEC, as well as the company's subsequently filed Quarterly Reports on Form 10–Q and Current Reports on Form 8–K. There can be no assurance that the actual results or developments anticipated by Entera will be realized or, even if substantially realized, that they will have the expected consequences to, or effects on, Entera. Therefore, no assurance can be given that the outcomes stated or implied in such forward–looking statements and estimates will be achieved. Entera cautions investors not to rely on the forward–looking statements Entera makes in this press release. The information in this press release is provided only as of the date of this press release, and Entera undertakes no obligation to update or revise publicly any forward–looking statements, whether as a result of new information, future events or otherwise, except to the extent required by law.

ENTERA BIO LTD.

CONSOLIDATED BALANCE SHEETS
(U.S. dollars in thousands, except share data)
(Unaudited)
September 30 December 31
2022 2021
Cash and cash equivalents 14,323 24,892
Accounts receivable and other current assets 867 437
Property and equipment, net 152 156
Other assets, net 198 502
Total assets 15,540 25,987
Accounts payable and other current liabilities 1,193 3,161
Total non current liabilities 35 261
Total liabilities 1,228 3,422
Total shareholders' equity 14,312 22,565
Total liabilities and shareholders' equity 15,540 25,987


ENTERA BIO LTD.

CONSOLIDATED STATEMENTS OF OPERATIONS
(U.S. dollars in thousands, except share and per share data)

Three Months ended September 30,
2022 2021
REVENUES 8 140
COST OF REVENUES 6 65
GROSS PROFIT 2 75
OPERATING EXPENSES:
Research and development 1,413 1,771
General and administrative 1,460 1,535
Other income (6 ) (11 )
TOTAL OPERATING EXPENSES 2,867 3,295
OPERATING LOSS 2,865 3,220
FINANCIAL EXPENSES, net 8 7
LOSS BEFORE INCOME TAX 2,873 3,227
INCOME TAX (BENEFIT) EXPENSE 194 (13 )
NET LOSS 3,067 3,214
LOSS PER SHARE BASIC AND DILUTED 0.11 0.11
WEIGHTED–AVERAGE NUMBER OF SHARES OUTSTANDING USED IN COMPUTATION OF BASIC AND DILUTED LOSS PER SHARE 28,809,922 28,680,833

___________________________
1
Triangle Insights Group June 2022 Analysis, EB613 Osteoporosis Opportunity


GLOBENEWSWIRE (Distribution ID 8694353)

Making the UN Charter a Reality: Towards a New Approach to Development Cooperation?

Credit: UN Photo/Amanda Voisard

By A.H. Monjurul Kabir
NEW YORK, Nov 10 2022 – We are living in a world where both our bilateral and multilateral achievements, consensuses on human rights and social justice, and our resolve to public good are being tested like never before.

Now, more than ever, we need to bring to life the values and principles of the UN Charter in every corner of the world. Due to the powers vested in its Charter and its unique international character, the UN can act on the issues confronting humanity, including:

    • Maintain international peace and security
    • Protect human rights
    • Deliver humanitarian aid
    • Promote sustainable development
    • Uphold international law

Given my own personal trajectory in human rights advocacy and development cooperation, let me focus on aspects of sustainable development and consider whether we need to change and adopt any new approach to it to end extreme poverty, reduce inequalities, and rescue the Sustainable Development Goals (SDGs) from exclusionary practices.

Development or Sustainable Development must be inclusive: In fact, inclusion at the heart of Development Cooperation. Inclusive development is the concept that every person, regardless of their identity, is instrumental in transforming their societies.

Development processes that are inclusive yield better outcomes for the communities that embark upon them. The UN was created to promote the rights and inclusion of marginalized and underrepresented populations in the development process and leads the UN’s response to addressing the needs and demands of those in in adversity and youth.

Therefore, the UN implements activities that combat stigma and discrimination, promote empowerment and inclusion of marginalized or underrepresented groups, and improve the lives of populations in high-risk situations.

It is important that we also adopt this in institutional and management settings: For example, UN Asia Network for Diversity and Inclusion (UN-ANDI) recently conducted its first survey on Racism and Racial Discrimination in five languages.

The survey was intended to capture data reflecting the Asian perspective in the UN system. It is planning to issue a report on the survey’s findings to support and address many critical issues of racism and racial discrimination. There are other networks who are addressing different elements of intersectionality including but not limited to, gender, disability, ethnicity, identity etc.

So, the world and its challenges have become much more intersectional, which calls for a robust and intersectional approach to development cooperation.

Intersectional Approach: An intersectionality lens allows us to see how social policy may affect people differently, depending on their specific set of ‘locations,’ and what unintended consequences particular policies may have on their individual lives.

By listening to the most marginalized and/or disadvantaged groups of a community, development organizations can help combat oppression at all levels of society and rebuild communities from the ground up.

Take the example of Persons with Disabilities. They are not a homogenous group, and this should be reflected in our policy advocacy and communications by considering intersectionality—the intersection of disability together with other factors, such as gender, age, race, ethnicity, sexual orientation, refugee, migrant or asylum seeker status.

For example, a person with disability also has a gender identity, may come from an Indigenous group and be young, old, a migrant or live in poverty.

At the UN System, it is time to adopt an intersectional approach in our development cooperation, policy advocacy, programming, operational support, planning and budgeting. An intersectional approach considers the historical, social, and political context and recognizes the unique experience of the individual based on the intersection of all relevant grounds.

This approach allows the experience of discrimination, based on the confluence of grounds involved, to be acknowledged and remedied. Using an intersectionality lens to approach our development practice means moving beyond the use of singular categories to understand people and groups and embracing the notion of inseparable and interconnected sets of social ‘locations’ that change through time, vary across places, and act together to shape an individual’s life experience and actions.

This would go a long way to contribute to the SDGs’ Leave No One Behind principle (LNOB). The new approach calls for invigorating existing practices, making them more innovative, effective, and efficient.

Innovation: We need to think of innovative approaches and instruments to attract and channel new resources to finance our developmental aspirations, as outlined in the 2030 SDGs now more than ever.

Reliable and well-administered development financial institutions with a well-defined mandate and sound governance framework will continue to be an important vehicle to accelerate inclusive economic and social development.

They can create new channels to crowd-in the private sector. Moreover, they can play a catalytical role by generating new knowledge, convening stakeholders, and providing technical assistance to build capacity in the private and public sectors. Mutual collaboration between and across public and private sector is critical to harness the full potential of innovation and innovative approaches.

Let us not forget new media’s growing impact on both inclusive participation leveraging innovative practices.

New Media: New media, including mobile and social media, could help demystify international institutions and encourage participation. The new media is also critical to widen the breadth of accessibility for persons with disabilities or those who live in rural and/or remote, hard to reach areas.

Alongside this, there could be more regular interactions by the leadership of intergovernmental organisations with multi-stakeholders including civil society, organisations of persons with disabilities, and the media, and the creation of accessible databases of statistical and other information and knowledge on their work.

Notwithstanding the Ukraine war, work at the UN continues. The world body can and should continue to play a constructive role in both development cooperation, crisis management, peace building, and post-conflict stabilization. It should continue to focus on crises from Afghanistan to Mali and Ukraine itself.

However, it must explore new and innovative and intersectional ways to support inclusive development, climate justice and resilience, peacekeeping, and other global and regional key priorities.

Otherwise, the SDGs will not be even near to their desired destination in 2030 or beyond.

Dr. A.H. Monjurul Kabir, currently Global Policy and UN System Coordination Adviser and Team Leader for Gender Equality, Disability Inclusion, and Intersectionality at UN Women HQ in New York, is a political scientist and senior policy and legal analyst on global issues and Asia-Pacific trends.

For policy and academic purposes, he can be contacted at monjurulkabir@yahoo.com and followed on twitter at mkabir2011

This article is from a blog based on a speech delivered by the author, in his personal capacity, at an event commemorating the UN’s 77th anniversary organized by UN-ANDI– a New York-based global network of like-minded Asian staff members of the UN system who strive to promote a more diverse and inclusive culture and mindset within the UN.

IPS UN Bureau

 


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‘Tactical’ Nuclear Weapons Could Unleash Untold Damage, Experts Warn

Nuclear experts warn that ‘tactical’ nuclear weapons could have devastating death toll and destruction. This photo shows the war damage in Borodianka, Kyiv Oblast. Photo: Oleksandr Ratushniak / UNDP Ukraine

Nuclear experts warn that ‘tactical’ nuclear weapons could have devastating death toll and destruction. This photo shows the war damage in Borodianka, Kyiv Oblast. Photo: Oleksandr Ratushniak / UNDP Ukraine

By Ed Holt
BRATISLAVA, Nov 10 2022 – Since the start of Russia’s invasion of Ukraine, the conflict’s potential to escalate to the use of nuclear weapons has been highlighted by political analysts and military experts alike.

Now growingly bellicose rhetoric from Russian president Vladimir Putin, particularly following the illegal annexations of four parts of Ukraine at the end of September, has raised fears he may be seriously considering using them. He has been quoted in September this year as saying that Russia would use “all available means to protect Russia and our people”, but last month said there was no need to consider the use of nuclear weapons. This week Russia ordered troops to withdraw from the Dnieper River’s west bank near the southern city of Kherson.

But while much of the media debate around this prospect has focused on the expected use of a so-called low-yield “tactical” nuclear weapon and what this might mean strategically for either side in the war, anti-nuclear campaigners say any discussion should be reframed to reflect the devastating reality of what the use of even the smallest weapons in modern nuclear arsenals would mean.

They say that even if only one such bomb was dropped, be it in Ukraine or in any other conflict, the consequences would cause a country – if not a continent-wide catastrophe, with horrific immediate and long-term health effects and a subsequent humanitarian disaster on a scale almost certainly not seen before.

Moreover, they say, a single strike would almost certainly be met with a similar response, quickly igniting a full-scale nuclear war that would threaten much of human life on earth.

“There is no conceivable reality in which a nuclear weapon is used, and life goes on as normal. It is very, very likely that there would be escalation and additional nuclear weapons used, but even the use of one nuclear weapon would break a decades-long taboo on the use of the most catastrophic, horrific weapon ever created,” Alicia Sanders-Zakre, Research, and Policy Coordinator,  at the International Campaign to Abolish Nuclear Weapons (ICAN) told IPS.

“We have already seen the global impacts of the war in Ukraine just using conventional weapons, including worldwide rising inflation, and energy and food shortages. But the use of a nuclear weapon would really have consequences beyond what any of us can imagine,” she added.

Since the bombing of Hiroshima and Nagasaki in 1945 – the only time nuclear weapons have been used in conflict – a number of states have built up nuclear arsenals, including bombs many times more powerful than those dropped on the two Japanese cities.

But they also include bombs that can be set to have varying explosive yields -which are measured in kilotons – including potentially in just single figures. For comparison, the devices dropped on Hiroshima and Nagasaki had yields of around 15 kilotons.

These lower yield bombs are, unlike strategic nuclear weapons with yields in the hundreds of kilotons that, are specifically meant to cause mass destruction and serve a deterrent purpose, designed for use on a battlefield to counter overwhelming conventional forces.

The strategic thinking behind their use is that they could cause maximum damage to enemy troops in specific areas without the wider massive destruction caused by larger bombs.

This does not mean, though, that tactical nuclear weapons are not devastatingly lethal – an estimated 130,000 people were killed by the atomic bomb dropped on Hiroshima, while NUKEMAP predicts that even a 5-kiloton bomb detonation on Kyiv would leave more than 90,000 people dead, and injured.

Campaigners against nuclear weapons worry the global public is not being made properly aware of the scale of the loss of life and ecological damage which would be wrought by the use of such a weapon.

“There has been a lot of discussion about using a tactical nuclear bomb in Ukraine. But the use of the word ‘tactical’ is no more than a rebranding exercise to make a nuclear weapon sound like a conventional one,” Dr Ruth Mitchell, Board Chair of the International Physicians for the Prevention of Nuclear War (IPPNW), told IPS.

“A tactical nuclear weapon would be about the same size as the one dropped on Hiroshima and Nagasaki, and we don’t need to imagine what the effects would be; we have already seen them,” she added.

The death toll itself would be massive, but authorities would also have to deal with radioactive fallout possibly contaminating large areas, while the event itself would trigger massive population dislocation.

And a report by ICAN also shows that even the most advanced healthcare systems would be unable to provide any effective response in such a situation, highlighting the likely destruction of local healthcare facilities and staff and pointing out that the 1945 atomic bombing of Hiroshima destroyed 80% of its hospitals and killed almost all its doctors and nurses.

Healthcare staff in Ukraine have told IPS that preparations are being made at hospitals and healthcare facilities to respond to a nuclear attack, including plans for reprofiling wards and forming special teams of emergency staff to treat those affected both directly in the area of any strike and where needed in other parts of the country.

Meanwhile, authorities in cities have said potential evacuation centres have been set up, and supplies of potassium iodide, which can help block the absorption of harmful radiation by the thyroid gland, have been secured to be distributed if needed.

Some doctors have said they are also counting on international help for Ukraine’s healthcare response if the worst to happen.

But Mitchell said while admirable, such efforts were likely to be of little help.

“It is naïve to think there is a terrible amount that we can do in the event of use of a nuclear weapon against civilian populations, which is the only way any will ever be used. They will be used strategically, i.e., on a populous city. No one’s going to be dropping them in a paddock. It would be a massive disaster,” she said.

Some Ukrainian doctors admit they may not be able to provide much help.

“If the hospital is hit with a bomb then there won’t be much we can do,” Roman Fishchuk, a doctor at the Central City Clinical Hospital in Ivano-Frankivsk in western Ukraine told IPS.

Another key issue, Mitchell said, is the fact that any use of a nuclear weapon in a conflict situation, be it in Ukraine or anywhere else, would almost certainly not be left in isolation.

There would likely be a response in kind, followed by a very rapid escalation to nuclear war and multiple missile detonations, with terrifying planet-wide consequences, she said.

A recent report by experts studying the potential effects of a nuclear conflict concluded that while more than 5 billion could die from a war between the United States and Russia, “even a war between India and Pakistan using less than 3% of the global nuclear arsenal” could result in famine for a third of Earth.

ICAN’s Sanders-Zakre explained that the current situation in Ukraine has only highlighted the need for nuclear weapons to be abolished across the world, and how more attention needs to be paid to experts pointing out their potential for civilisation-threatening destruction.

“What this shows is that we really need to listen to medical professionals, and organisations like IPPNW. They have been warning for decades about the consequences of using nuclear weapons, and we have learned from the catastrophic Covid-19 pandemic that it is essential that we listen to professionals and experts and take their expertise seriously, and it’s the same in this case with the use of a nuclear weapon,” she said.

Meanwhile, in Ukraine, people are preparing for the worst. Some have begun stocking rooms converted into bomb shelters with food and other supplies they believe will help them ride out the aftermath of a nuclear strike. Others have been buying potassium iodide tablets.

But some say they have little faith they would survive any such attack and are just hoping it will never happen.

“The Health Ministry has given out advice on what to do if there is a nuclear attack, and I know some of the basic things to do, but I don’t feel like I’m prepared to deal with something like this if it happens. I just hope we won’t have to deal with this. It would be horror,” 23-year-old Kyiv resident Viktoria Marchenko (NOT REAL NAME) told IPS.

IPS UN Bureau Report

 


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