Minovia Therapeutics Announces FDA Clearance of IND Application for a Phase Ib Clinical Trial of MNV-201 in Low Risk Myelodysplastic Syndrome

MNV–201 is a mitochondrial cell therapy product composed of autologous hematopoietic stem cells enriched with allogeneic mitochondria

In pre–clinical studies, MNV–201 demonstrated improved engraftment and bone marrow reconstitution potential of patient derived hematopoietic stem cells

In vitro data also demonstrated improved ability to differentiate to erythroid cells, supporting potential for improvement in biomarkers of anemia

HAIFA, Israel, Sept. 26, 2024 (GLOBE NEWSWIRE) — Minovia Therapeutics Ltd, a clinical stage biopharmaceutical company advancing mitochondrial cell therapies for primary and secondary mitochondrial diseases, today announced that the U.S. Food and Drug Administration (FDA) has cleared its Investigational New Drug (IND) application for MNV–201, an autologous hematopoietic stem cell product augmented with allogeneic mitochondria. The IND supports the initiation of a Phase Ib dose exploration clinical trial of MNV–201 in patients with Low Risk Myelodysplastic Syndrome (MDS).

Anemia is a common and serious symptom in patients with low–risk myelodysplastic syndrome (LR–MDS), affecting almost 90% of cases and is often the primary characteristic of the disease. Anemia in MDS can have a negative impact on quality of life and may correlate with decreased progression–free survival and overall survival. 

“The FDA’s clearance of our IND marks an important achievement for Minovia, allowing us to clinically evaluate our allogeneic mitochondrial cell therapy approach and proceed with the Phase Ib clinical program for this first–in–class allogeneic mitochondrial therapy for low risk MDS patients,” said Natalie Yivgi Ohana, PhD, CEO of Minovia. “We are pleased to have safely dosed two MDS patients enrolled in an ongoing study under the Israeli Ministry of Health. We look forward to treating additional patients under this IND, as well as to learning about the potential of MAT to improve anemia in this patient population.”

The Phase Ib clinical trial is an open–label, dose exploration study to evaluate the safety and efficacy of MNV–201 in subjects with low risk MDS. This trial will continue our campaign to evaluate dose exploration and safety of single or repeat dosing of MNV–201. The trial will also enable assessment of efficacy in improving anemia and durability of response. The study is expected to enroll at least three patients each in the low, medium and high dose cohorts, and up to a total of 15 patients in total. For more information visit clinicaltrials.gov.

About MNV–201
MNV–201 is an autologous hematopoietic stem cell product enriched with allogeneic mitochondria. MNV–201 aims to restore mitochondrial function in low risk MDS patient hematopoietic stem cells, resulting in improved differentiation to erythroid lineage with the potential to improve anemia. Preclinical research suggests the potential for safe dosing with low immunogenicity risk and scalable manufacturing to address the significant number of patients who are potentially eligible for MNV–201 therapy.

About Minovia Therapeutics
Minovia Therapeutics Ltd. is a clinical stage biotechnology company advancing mitochondrial cell therapies for primary–genetic and age–related mitochondrial diseases. Minovia's clinical stage product candidate, MNV–201, is composed of mobilized peripheral blood, autologous CD34+ cells enriched with allogeneic, cryopreserved placental derived mitochondria, produced by Minovia's proprietary Mitochondrial Augmentation Technology (MAT). The enrichment of hematopoietic stem cells with healthy and functional mitochondria aims to restore stem cells function of patients suffering mitochondrial dysfunction, caused both by mtDNA mutations or deletions in pediatric patients suffering from primary mitochondrial diseases, or in adults with age–related bone marrow failure disorders. MNV–201 is currently in clinical studies for pediatric patients with single–large scale mtDNA deletion syndromes (Pearson Syndrome and Kearn Sayre Syndrome) with four patients successfully dosed; and in Low Risk Myelodysplastic Syndrome. For more information, please visit www.minoviatx.com or follow the Company LinkedIn.

About Low Risk Myelodysplastic Syndrome

Myelodysplastic syndromes (MDS) are a group of bone marrow failures that occur when the blood–forming cells in the bone marrow become abnormal leading to an abnormal differentiation and production of one or more blood cell types. Patients with MDS collectively have a high symptom burden and are also at risk of death from complications of cytopenias or progression to acute myeloid leukemia (AML). MDS is generally a disease that develops with aging; the median age at diagnosis of MDS is ~70 years.

Mitochondrial Dysfunction in MDS: Scientific literature shows a correlation between mitochondrial dysfunction and MDS progression. It is known that ineffective hematopoiesis in MDS results from increased susceptibility of clonal myeloid progenitors to apoptosis. This may be triggered by intrinsic factors, such as mitochondrial polarization due to iron retention in ringed sideroblasts. A subset of MDS patients present with sideroblastic anemia, a phenotype common in Pearson Syndrome patients and which implicates mitochondrial dysfunction of HSPCs as part of the pathology of MDS.

Contact Information: Natalie Yivgi Ohana, Co–Founder and CEO

Phone: +972–74–7039954

Email: info@minoviatx.com


GLOBENEWSWIRE (Distribution ID 9237236)

Rock & Roll Hall of Fame stellt Liste der Ehrengäste für die Einführungszeremonie 2024 vor

Dr. Dre, Demi Lovato, Dua Lipa, James Taylor, Jelly Roll, Julia Roberts, Keith Urban, Kenny Chesney und weitere schließen sich der hochkarätigen Besetzung für die höchste Auszeichnung der Musik an

Einführungsfeier Live–Streams auf Disney+ am Samstag, 19. Oktober

NEW YORK, Sept. 26, 2024 (GLOBE NEWSWIRE) — Die Rock & Roll Hall of Fame Foundation freut sich, eine außergewöhnliche Reihe von Ehrengästen bekannt zu geben, die bei der mit Spannung erwarteten Aufnahmezeremonie am 19. Oktober 2024 im Rocket Mortgage FieldHouse in Cleveland die Bühne betreten werden, um die diesjährigen Aufgenommenen vorzustellen, zu präsentieren und zu ehren. Zu den auftretenden Künstlern gehören Mary J. Blige, Cher, die Dave Matthews Band, Foreigner, Peter Frampton, Kool & the Gang und Dionne Warwick, die einen unvergesslichen Abend voller Musik und Feierlichkeiten versprechen.

Die Einführungszeremonie wird am Samstag, dem 19. Oktober, um 19:00 Uhr (Ortszeit) live von Küste zu Küste auf Disney+ übertragen. EDT/18:00 Uhr CDT/17:00 Uhr MDT/16:00 Uhr PDT) und wird nach der Zeremonie als Stream verfügbar sein. ABC wird am MITTWOCH, 1. JANUAR 2025 (20:00–23:00 Uhr EST) eine Sondersendung zur Hauptsendezeit mit dem Titel „2024 Rock & Roll Hall of Fame Induction Ceremony“ ausstrahlen, die Höhepunkte und herausragende Momente der Zeremonie zeigt und am nächsten Tag auf Hulu und Disney+ verfügbar.

Zu den neu bestätigten Moderatoren und Künstlern gehören:

  • Busta Rhymes
  • Chuck D
  • Dr. Dre
  • Demi Lovato
  • Dua Lipa
  • Ella Mai
  • James Taylor
  • Jelly Roll
  • Julia Roberts
  • Keith Urban
  • Kenny Chesney
  • Lucky Daye
  • Mac McAnally
  • Method Man
  • Roger Daltrey
  • Sammy Hagar
  • Slash
  • The Roots

„Jedes Jahr treten die größten Namen aus Musik, Film und Kultur bei unserer Zeremonie auf die Bühne, um den legendären Aufgenommenen Tribut zu zollen, deren Musik Generationen geprägt hat,“ sagte John Sykes, Vorsitzender der Rock & Roll Hall of Fame Foundation. „Das sind einmalige Momente, die für immer in Erinnerung bleiben werden.“

Weitere Moderatoren und Künstler werden im Vorfeld der Show bekannt gegeben.

Die Einführungszeremonie in die Rock & Roll Hall of Fame ehrt die diesjährigen Eingeführten: Mary J. BligeCherDave Matthews BandForeignerPeter FramptonKool & the GangOzzy Osbourne, und A Tribe Called Quest, sowie Alexis Korner, John Mayall, und Big Mama Thornton für musikalischen Einfluss und Jimmy BuffettMC5Dionne Warwick und Norman Whitfield für musikalische Exzellenz sowie Suzanne De Passe für den Ahmet–Ertegun–Preis. Die diesjährige Show wird von Joel Gallen und Tenth Planet Productions produziert und geleitet. Die ausführenden Produzenten sind John Sykes, Joel Peresman und Joel Gallen.

Weitere Informationen zur 39. jährlichen Einführungszeremonie in die Rock & Roll Hall of Fame finden Sie unter rockhall.com.

Über die Rock & Roll Hall of Fame
Rock 'n' Roll entstand aus der Kollision von Rhythm 'n' Blues, Country und Gospel und ist ein Geist, der alle einschließt und sich ständig verändert. Die Rock & Roll Hall of Fame feiert den Klang der Jugendkultur und ehrt die Künstler, deren Musik uns alle verbindet. Wir erzählen Geschichten von Menschen, Ereignissen und Liedern, die unsere Welt prägen, durch digitale Inhalte, innovative Ausstellungen, Live–Musik, ansprechende Programme und unsere jährliche Einführungszeremonie. Wir fördern bewusst ein vielfältiges und gerechtes gemeinnütziges Museum, das Kreativität und Innovation fördert und begrüßt. Als Führungspersönlichkeiten in der Gemeinschaft schätzen, stärken und respektieren wir alle Menschen. Schließen Sie sich den Millionen an, die Rock 'n' Roll genauso lieben wie Sie. Besuchen Sie uns in Cleveland, Ohio, oder auf rockhall.com und folgen Sie uns auf Facebook (@rockandrollhalloffame), Instagram (@rockhall), Twitter (@rockhall), TikTok (@RockHallFame) und YouTube (youtube.com/rockhall).

Medienkontakte

ALISON BROD MARKETING + COMMUNICATIONS
Dara Schopp Helitzer
rrhof@abmc–us.com

ROCK & ROLL HALL OF FAME
J.R. Johnson
jjohnson@rockhall.org

ABC
Sarah Castellvi
sarah.castellvi@disney.com

Disney+
Shelby Cotten
shelby.b.cotten@disney.com

Ein Foto zu dieser Ankündigung ist verfügbar unter https://www.globenewswire.com/NewsRoom/AttachmentNg/bf6953cf–db45–4a8c–b0fa–b2878ac1f83b


GLOBENEWSWIRE (Distribution ID 9237229)

Le Rock & Roll Hall of Fame dévoile la liste des invités d’honneur pour sa cérémonie d’intronisation 2024

Dr. Dre, Demi Lovato, Dua Lipa, James Taylor, Jelly Roll, Julia Roberts, Keith Urban, Kenny Chesney et bien d’autres rejoignent la programmation de stars qui seront présentes pour la remise de plus haute distinction musicale

La cérémonie d’intronisation sera diffusée en direct sur Disney+ le samedi 19 octobre

NEW YORK, 26 sept. 2024 (GLOBE NEWSWIRE) — La Fondation Rock & Roll Hall of Fame est ravie de dévoiler la programmation extraordinaire des invités d’honneur qui monteront sur scène afin de se produire, de présenter et d’honorer les intronisés de cette année lors de la très prestigieuse Cérémonie d’intronisation prévue le 19 octobre 2024 au Rocket Mortgage FieldHouse à Cleveland. Parmi les intronisés qui se produiront lors de cette soirée riche en musique et en célébration qui promet d’être inoubliable, on peut citer Mary J. Blige, Cher, Dave Matthews Band, Foreigner, Peter Frampton, Kool & the Gang ou encore Dionne Warwick.

La cérémonie d’intronisation sera diffusée en direct dans tout le pays sur Disney+ le samedi 19 octobre (à 19 h 00 Heure avancée de l’Est/18 h 00 Heure d’été du centre des États–Unis/17 h 00 Heure d’été des Montagnes Rocheuses/16 h 00 Heure d’été du Pacifique), et sera disponible en streaming après la clôture. ABC diffusera son émission spéciale en première partie de soirée, « Cérémonie d’intronisation au Rock & Roll Hall of Fame 2024 », qui réunira le meilleur des performances et les moments forts de la cérémonie le mercredi 1er janvier 2025 (de 20 h 00 à 23 h 00 Heure de l’Est), disponible le lendemain sur Hulu et Disney+.

Parmi les présentateurs et artistes dont la présence a été récemment confirmée, on retrouve :

  • Busta Rhymes
  • Chuck D
  • Dr. Dre
  • Demi Lovato
  • Dua Lipa
  • Ella Mai
  • James Taylor
  • Jelly Roll
  • Julia Roberts
  • Keith Urban
  • Kenny Chesney
  • Lucky Daye
  • Mac McAnally
  • Method Man
  • Roger Daltrey
  • Sammy Hagar
  • Slash
  • The Roots

« Chaque année, les plus grands noms de la musique, du cinéma et de la culture se retrouvent sur scène lors de notre cérémonie afin de rendre hommage aux intronisés de renom qui ont inspiré des générations entières avec leur musique », déclare John Sykes, Président de la Fondation Rock & Roll Hall of Fame. « Ce sont des moments inoubliables qui n’arrivent qu’une fois dans une vie. »

D’autres noms de présentateurs et artistes seront dévoilés avant la date de la cérémonie.

La cérémonie d’intronisation du Rock & Roll Hall of Fame met à l’honneur les intronisés de cette année : Mary J. BligeCherDave Matthews BandForeignerPeter FramptonKool & the GangOzzy Osbourne, et A Tribe Called Quest, ainsi qu’Alexis Korner, John Mayall, et Big Mama Thornton dans la catégorie influence musicale, et Jimmy BuffettMC5Dionne Warwick, et Norman Whitfield dans la catégorie excellence musicale, mais aussi Suzanne De Passe pour le prix Ahmet Ertegun. Cette année, le spectacle sera produit et réalisé par Joel Gallen et Tenth Planet Productions, avec comme producteurs exécutifs John Sykes, Joel Peresman et Joel Gallen.

Pour en savoir plus sur la 39e cérémonie annuelle d’intronisation du Rock & Roll Hall of Fame, rendez–vous sur rockhall.com.

À propos du Rock & Roll Hall of Fame
Né de la fusion entre le rhythm & blues, la country et le gospel, le rock & roll est un genre musical inclusif, en constante évolution. Le Rock & Roll Hall of Fame célèbre la musique emblématique de la culture jeune, et rend hommage aux artistes dont les chansons font vibrer chacun d’entre nous. Nous partageons les histoires de personnes, d’événements et de chansons qui ont façonné notre monde via du contenu numérique, des expositions d’avant–garde, de la musique live, des programmes attractifs et notre cérémonie d’intronisation annuelle. Nous promouvons volontairement un musée à but non lucratif diversifié et équitable qui encourage et accueille la créativité et l’innovation. En tant que leader au sein de la communauté, nous sommes attachés à la valorisation, à l’autonomisation et au respect de toutes les personnes. Rejoignez des millions d’amateurs de rock & roll tels que vous. Rendez–nous visite à Cleveland, Ohio ou sur rockhall.com et suivez–nous sur Facebook (@rockandrollhalloffame), Instagram (@rockhall), Twitter (@rockhall), TikTok (@RockHallFame) et YouTube (youtube.com/rockhall).

Contacts Médias

ALISON BROD MARKETING + COMMUNICATIONS
Dara Schopp Helitzer
rrhof@abmc–us.com

ROCK & ROLL HALL OF FAME
J.R. Johnson
jjohnson@rockhall.org

ABC
Sarah Castellvi
sarah.castellvi@disney.com

Disney+
Shelby Cotten
shelby.b.cotten@disney.com

Une photo accompagnant cette annonce est disponible à l’adresse suivante : https://www.globenewswire.com/NewsRoom/AttachmentNg/bf6953cf–db45–4a8c–b0fa–b2878ac1f83b


GLOBENEWSWIRE (Distribution ID 9237229)

Bitdeer Completes Testing of its Latest SEAL02 Bitcoin Mining Chip

SINGAPORE, Sept. 26, 2024 (GLOBE NEWSWIRE) — Bitdeer Technologies Group (NASDAQ: BTDR) (“Bitdeer” or the “Company”), a world–leading technology company for blockchain and high–performance computing, today announced the successful testing of its latest Bitcoin mining chip, SEAL02, following tape–out.

SEAL02 uses one of the most advanced process nodes in partnership with TSMC, a world–leading semiconductor foundry. An exceptional power efficiency ratio of 13.5 J/TH – while running at low voltage, ultra power–saving mode – was indicated in SEAL02 chip’s verification and prototype tests, achieving the power efficiency milestone outlined in the SEALMINER technology roadmap announced in June 2024.

Linghui Kong, Chief Business Officer of Bitdeer, commented, “We are thrilled about achieving SEALMINER’s power efficiency target as reflected in our roadmap. Our ongoing commitment to R&D is making possible innovative and superior solutions that will set new benchmarks for efficiency and transparency to benefit the wider mining ecosystem.”

SEAL02 will be integrated into the Company’s upcoming SEALMINER A2 mining machines, with mass production scheduled to commence in November 2024.

Additionally, R&D work on the Company’s upcoming chip, SEAL03, is ongoing and the Company’s product release milestone is on track.

Bitdeer has a full–fledged team of professional engineers dedicated to R&D across key domains, including ASIC design, algorithm development, platform architecture, software and hardware. The Company will continue to work alongside its customers in contributing to the security of the Bitcoin decentralized network.

About Bitdeer Technologies Group

Bitdeer is a world–leading technology company for blockchain and high–performance computing. Bitdeer is committed to providing comprehensive computing solutions for its customers. The Company handles complex processes involved in computing such as equipment procurement, transport logistics, datacenter design and construction, equipment management, and daily operations. The Company also offers advanced cloud capabilities to customers with high demand for artificial intelligence. Headquartered in Singapore, Bitdeer has deployed datacenters in the United States, Norway, and Bhutan. To learn more, visit https://www.bitdeer.com/ or follow Bitdeer on X @ BitdeerOfficial and LinkedIn @ Bitdeer Group.

Investors and others should note that Bitdeer may announce material information using its website and/or on its accounts on social media platforms, including X, formerly known as Twitter, Facebook, and LinkedIn. Therefore, Bitdeer encourages investors and others to review the information it posts on the social media and other communication channels listed on its website.

Forward–Looking Statements

Statements in this press release about future expectations, plans, and prospects, as well as any other statements regarding matters that are not historical facts, may constitute “forward–looking statements” within the meaning of The Private Securities Litigation Reform Act of 1995. The words “anticipate,” “look forward to,” “believe,” “continue,” “could,” “estimate,” “expect,” “intend,” “may,” “plan,” “potential,” “predict,” “project,” “should,” “target,” “will,” “would” and similar expressions are intended to identify forward–looking statements, although not all forward–looking statements contain these identifying words. Actual results may differ materially from those indicated by such forward–looking statements as a result of various important factors, including factors discussed in the section entitled “Risk Factors” in Bitdeer’s annual report on Form 20–F, as well as discussions of potential risks, uncertainties, and other important factors in Bitdeer’s subsequent filings with the U.S. Securities and Exchange Commission. Any forward–looking statements contained in this press release speak only as of the date hereof. Bitdeer specifically disclaims any obligation to update any forward–looking statement, whether due to new information, future events, or otherwise. Readers should not rely upon the information on this page as current or accurate after its publication date.

Contact:

Public Relations
Wachsman
Bee Shin
bitdeer@wachsman.com


GLOBENEWSWIRE (Distribution ID 9237034)

Solar Panels Aim to Protect Mexican Family Farming

The public National Autonomous University of Mexico operates a demonstration agrovoltaic plot to study the effects of the mixture of solar energy and crops in the town of San Miguel Topilejo, in the south of Mexico City. Credit: Emilio Godoy / IPS

The public National Autonomous University of Mexico operates a demonstration agrovoltaic plot to study the effects of the mixture of solar energy and crops in the town of San Miguel Topilejo, in the south of Mexico City. Credit: Emilio Godoy / IPS

By Emilio Godoy
SAN MIGEL TOPILEJO, Mexico, Sep 26 2024 – Verónica Molina, an indigenous Comcaac woman, first came into contact with solar energy in 2016, when she travelled to India for training on communal photovoltaic facilities. This later enabled her to take part in the installation of the first solar systems and family vegetable gardens in her community, Desemboque del Seri, in northern Mexico.

Later on, she was invited to the project Energy, Water and Food Security for Indigenous Peoples in Semi-Arid Coastal Regions of Northern Mexico, sponsored by the governmental National Council of Humanities, Science and Technology (Conahcyt), which began in 2022.

“We plant vegetables, because there are no other seeds to use. They are for self-consumption. With the panels, we pay less for energy, and with the gardens we save money on vegetables,” the solar activist told IPS from Desemboque del Seri, some 1,900 kilometres from Mexico City.

“We realised that they had health, economy, food, and land issues. We looked for comprehensive solutions, aligned with the budget. They have the sea or the desert, it’s an extremely arid place,” Rodolfo Peón.
In addition to producing their own electricity, the participating families harvest a variety of vegetables in Desemboque and neighbouring Punta Chueca, Comcaac territories inhabited by some 1,200 people on the coast of the state of Sonora, and one of Mexico’s 69 indigenous peoples, who also fish.

While the panels cover between 25% and 75% of a household’s consumption, each of the more than 40 family gardens provides between 100 and 200 kilograms of vegetables for each of the two annual harvest seasons.

The region suffers from marginalisation, poverty and disease. In contrast, it receives a daily solar irradiation of 5.9 kWh/m2 and an annual rainfall of 200 millilitres, which makes seasonal agriculture difficult.

The initiative consists of a hybrid system that combines photovoltaic generation and food production, located under the panels to harness the sun, shade and dew that they capture during the night, which is in vogue in countries such as Germany, Brazil and the United States.

This eco-technology is still in its infancy in Mexico, and it is unknown how many systems are in operation in the country. The Mexican Agrovoltaic Network is preparing a census to determine their status.

In fact, the Strategic Plan on Climate Change for the Agri-Food Sector includes among its goals the use of solar panels for electricity generation.

Comcáac indigenous people have installed agrovoltaic systems, which combine solar energy and family gardens, in the Desemboque de los Seris community, in the northern Mexican state of Sonora. Credit: Courtesy of Rodolfo Peón

Comcáac indigenous people have installed agrovoltaic systems, which combine solar energy and family gardens, in the Desemboque de los Seris community, in the northern Mexican state of Sonora. Credit: Courtesy of Rodolfo Peón

Mitigation

“We realised that they had health, economy, food, and land issues. We looked for comprehensive solutions, aligned with the budget. They have the sea or the desert, it’s an extremely arid place,” Rodolfo Peón told IPS from Hermosillo, the capital of Sonora.

“We saw that agriculture was an alternative to improve their diet and provide electricity,” added the researcher from the Department of Industrial Engineering at the public University of Sonora, referring to the project in the Comcáac territory.

This is how the agrovoltaic scheme, the only low-cost solution for the area, came on the scene.

Funded by Conahcyt’s National Strategic Programmes with some 450,000 dollars, the project addresses the components of energy, water, food, health, biodiversity and territorial defence.

Since 2018, the government has been driving, with little success, for internal capacity (sovereignty) in food production for Mexico’s population of some 130 million people.

Mexico currently ranks 11th in the world in food production. During the first seven months of this year it exported more agri-foods than in the same period last year, although it also bought more, albeit in an agricultural balance with a surplus.

Mexico ranks 11th in the world in food and agricultural crop production, and has high agrovoltaic potential, with 20 million hectares planted and more than 10,000 megawatts of solar energy. Infographic: Sader

Mexico ranks 11th in the world in food and agricultural crop production, and has high agrovoltaic potential, with 20 million hectares planted and more than 10,000 megawatts of solar energy. Infographic: Sader

The country is highly vulnerable to the effects of the climate crisis, such as drought, rising temperatures and the spread of pests.

As a result, producers of maize, beans, wheat, coffee and other traditional products are already suffering the impacts of phenomena such as this year’s acute water shortages, and will suffer even more negative impacts in the long term, with consequences for quality of life, income and the rural environment.

Latin America’s second largest economy has around six million rural production units, of which 75% are less than five hectares in size and only 6% have more than 20 hectares, supporting some 20 million people.

In addition, 79% of electricity generation depends on fossil fuels, followed by wind (7%), photovoltaic (4.5%), hydroelectric (4.4%) and nuclear (3.7%). According to the Electricity Transition Law, the country should generate 35% of its electricity from alternative sources by 2024, but this is a distant goal.

The administration of outgoing President Andrés Manuel López Obrador, which began in December 2018 and will end on 1 October, put the brakes on energy transition in order to strengthen the state-owned Federal Electricity Commission, which burns gas for electricity generation, and Petróleos Mexicanos, thus favouring fossil fuels.

The country has agrovoltaic potential, with 20 million hectares of land under cultivation and more than 10,000 megawatts of photovoltaic power, 70% of which is in extensive facilities.

In the town of San Miguel Topilejo, in the south of Mexico City, the Sustainable and Educational Agrovoltaic Plot consists has ten crops sheltered under solar panels using drip irrigation. Credit: Emilio Godoy / IPS

In the town of San Miguel Topilejo, in the south of Mexico City, the Sustainable and Educational Agrovoltaic Plot consists has ten crops sheltered under solar panels using drip irrigation. Credit: Emilio Godoy / IPS

Hybrid experiments

At a height of four metres, six modules of photovoltaic panels capture solar energy which, after passing through a converter, will be transformed into electricity.  Sheltered by them, 24 beds house pumpkin, lettuce and tomato crops, which benefit from protective shade, and rainwater and night dew caught by the panels.

This takes place in the Sustainable and Educational Agrovoltaic Plot (Pase), located in a corner of the Center for Practical Teaching and Research in Animal Production and Health of the Faculty of Veterinary Medicine and Animal Science of the public National Autonomous University of Mexico (UNAM).

The centre is located in San Miguel Topilejo, a town in the municipality of Tlalpan, in the south of Mexico City.

At the facility visited by IPS, on the other side of a dirt road, stalled cattle graze while the photovoltaic system waits for the overcast skies to open up and bathe them in the sun’s nourishing rays.

On one side of the plot there are six more open-air beds to compare the results with those protected by the panels.

During an earlier tour of the facility, Aarón Sánchez, an academic at the Unam’s Institute of Renewable Energies and coordinator of the plot, explained that they are studying how crops develop under a photovoltaic roof that generates electricity.

He explained that they analyse their performance when there is a transpiration process in the lower part of the crops themselves, and the modules work at a lower temperature and higher efficiency.

Inaugurated in 2023, the Pase aims to increase the quality and quantity of agricultural products, generate green energy, reduce water consumption, and socialise new technologies among farmers.

The plot, which has a rainwater harvesting system with a 145 cubic metre tank to feed the drip irrigation system and temperature and humidity sensors, also involves the Mexico City government’s Ministry of Education, Science, Technology and Innovation.

An international consortium of institutions from the United States, France, Israel, Kenya, Morocco and Mexico is also participating.

Back in Sonora, Molina and Peón called for more support to expand the systems.

“We can ask for more support, because some families in the community have not had access to the agrovoltaic garden. Hopefully the project can be continued”, the community photovoltaic expert said.

Peón believes the results are promising, but much remains to be done.

“We hope that there will be a federal programme to support indigenous peoples. There has to be a change in the rules of the game (for people to generate their own energy in greater volumes),” he said.

“There needs to be synergy between the energy and agricultural sectors, so that we can see large-scale projects”, he added.

Rising Temperatures Devastate Agricultural Eden of India’s Kashmir Region

Four-fifths of Kashmir’s population depends on agriculture. Yet, this heatwave is devastating crops, including the famed saffron. Credit: Umar Manzoor Shah/IPS

Four-fifths of Kashmir’s population depends on agriculture. Yet, this heatwave is devastating crops, including the famed saffron. Credit: Umar Manzoor Shah/IPS

By Umar Manzoor Shah
SRINAGAR, India, Sep 26 2024 – Abdul Hameed Sheikh sowed his crop, working tirelessly for days in his paddy field.

The 52-year-old farmer, from central Kashmir’s Budgam area, religiously irrigated his 3-acre plot to keep the soil well hydrated. He waited for the rain, but days passed and it didn’t come.

What did, though, was scorching heat—temperatures surged like never before.

Every morning, Sheikh would walk his paddy field, noticing how the saplings had begun to turn into dry, dead twigs—slowly and definitively. As days passed, he noticed another worrisome trend. The land had developed cracks, generating dust as he passed by. 

“It was at that time when I was sure that the harvest wasn’t going to be as expected. The yearlong hard work is going to get wasted and I am completely helpless in such a scenario. This is utterly worrisome,” Sheikh told IPS.

This farmer was not alone in his worries. People in this farming district in the Himalayan region complained of extreme heat waves never before witnessed in Kashmir’s living memory.

“The temperatures touched even 40 °C here. In previous years, it would not cross even 32 °C,” says Abdul Salaam Malik, a farmer hailing from south Kashmir’s Shopian.

The protracted dry weather has stressed plants, said Professor Raihana Habib Kanth, Chief Scientist at the Faculty of Agriculture at Sheri Kashmir University of Agriculture Science and Technology (SKUAST) in Kashmir. “The prolonged dry weather has caused paddy crop tips to burn and vegetable plant leaves to dry,” she told IPS, noting that 3–5 liters of water are needed to produce 1 kg of rice.

A recent study published in Science Direct, ‘Time series analysis of climate variability and trends in Kashmir Himalaya,’ notes the region is extremely sensitive to “even small perturbations in climate” and the “shifting pattern in precipitation could have serious environmental implications that will greatly influence the food security and ecological sustainability of the region if the same trends persist.”

According to the meteorological office, the region’s capital, Srinagar, recorded a high of 36.2 °C on July 28 this year. This was the hottest July day since July 9, 1999, when the mercury had settled at 37 °C.

Government records show that 60 percent of agriculture in Kashmir depends on rainwater. However, recent years have seen some of the driest seasons on record. Credit: Umar Manzoor Shah/IPS

Government records show that 60 percent of agriculture in Kashmir depends on rainwater. However, recent years have seen some of the driest seasons on record. Credit: Umar Manzoor Shah/IPS

A study conducted in the year 2019 revealed that Kashmir’s average annual temperature has increased by 0.8˚C over 37 years (1980-2016), with recent summers breaking temperature records.

As per the government data, on August 17, 2020, the valley experienced its hottest August in 39 years, reaching 35.7˚C. The following year, on July 18, 2021, Srinagar saw its hottest July day in eight years, with temperatures hitting 35˚C.

The summer of 2022 was even hotter, with temperatures surpassing 35˚C in some areas, and March of that year was the hottest in 131 years. In September 2023, Srinagar recorded its hottest September day in 53 years at 34.2˚C.

This warming trend persisted into 2024, marked by an unusually dry and warm winter. January 2024, according to meteorological reports, was among the driest and warmest in the last 43 years. On May 23, Srinagar recorded the highest May temperature in at least a decade.

Apple growers in Kashmir are facing heavy losses due to the lack of rainfall and extreme heat. The deficit in rainfall and persistent heat waves threaten the livelihoods of those dependent on this vital crop. Credit: Umar Manzoor Shah/IPS

Apple growers in Kashmir are facing heavy losses due to the lack of rainfall and extreme heat. The deficit in rainfall and persistent heat waves threaten the livelihoods of those dependent on this vital crop. Credit: Umar Manzoor Shah/IPS

The Himalayan region has long been known to warm faster than the global average. The International Centre for Integrated Mountain Development (ICIMOD) noted in its first comprehensive report on the region, published in 2019, that even if global warming is limited to 1.5˚C, the Hindu Kush Himalayas (HKH) could see warming of at least 0.3˚C above this threshold.

A study published 2020 in Research Gate, ’21st Century-end Climate Scenario of Jammu and Kashmir Himalaya, India using Ensemble Climate Models,’ predicted that annual temperatures in Kashmir could rise by 4–7˚C by the end of the century, depending on future emissions.

The study noted that urbanization in Srinagar and other mountain settlements exacerbates heat, broader climatic changes remain the primary driver of rising temperatures.

Jasia Bashir, a research scholar at the University of Kashmir’s Centre of Excellence for Glacial Studies, told Dialogue Earth: “Urban areas feel intensified heat due to dense construction and reduced vegetation, but the entire region, including rural areas, is affected by the general [global] warming trend.”

Four fifths of Kashmir’s population is directly dependent on agriculture. The heat spell has left the farmers, including saffron farmers, wrecked.

Mohammad Ashraf Mir from Kashmir’s Pampore area shares his predicament, highlighting how the less rainfall and surging temperatures are compelling saffron farmers, including himself, to abandon farming forever.

Jehlum River in Kashmir shows drastically receding water. Credit: Umar Manzoor Shah/IPS

Jehlum River in Kashmir shows drastically receding water. Credit: Umar Manzoor Shah/IPS

“The irrigation facilities are nowhere. The land has become parched to the core. We have invested much in this crop and what we are getting in return is an insurmountable predicament. The time is coming when we will have to abandon this farming and do something else for a living,” Mir told IPS.

According to government records, approximately 60 percent of Kashmir’s agriculture relies on rainwater for irrigation. However, in recent years, the Kashmir Valley has experienced some of the driest seasons on record. The Meteorological Department reports that, over the past three years, the region’s mountain ranges received just 172 mm of snow, a significant drop from the average of 622 mm.

One in a hundred irrigation schemes have been impacted by the dry weather, according to government officials in the Irrigation and Flood Control (I&FC) department. The Jhelum River’s water level has decreased as a result. According to them, the Jhelum River’s overall water capacity has dropped by 30 percent.

So what of the future?

According to a detailed report prepared by Indian Network for Climate Change Assessment (INCCA) released in 2023, the two biggest issues facing Kashmir in the coming decades will be water stress and biodiversity loss brought on by climate change. It says that the region’s fisheries, forests, animals, species richness and water resources are all seriously threatened by climate change. Twenty percent of the region’s recognized biodiversity is supported by the numerous wetlands in Jammu and Kashmir, which are negatively impacted.

Among other farmers feeling the heat are the apple growers of Kashmir.

Several apple growers told IPS that the rainfall deficit and heat wave conditions are wreaking havoc on apple production and will cause heavy losses to the people associated with the apple trade.

Fayaz Ahmad Malik, President of the North Kashmir Apple Growers Association, calls the situation “alarming.”

He explains that the ongoing heat wave not only hampers fruit growth but also heightens the risk of pest and insect infestations.

“Dry weather can cause an increase in pest populations, which is a major threat to our apple orchards. The lack of sufficient moisture impacts fruit development and makes the orchards more susceptible to various diseases,” Malik stated.

Agricultural experts stress the importance of timely irrigation and effective water management to counter the negative effects of the dry spell.

“In these conditions, it becomes crucial for growers to manage orchard irrigation. Farmers should prioritize constructing borewells in their orchards to ensure adequate water supply,” they advised.

IPS UN Bureau Report

 


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World Governments, NGOs Announce $350m Investments in Sexual and Reproductive Health Services

Dr. Natalia Kanem, UNFPA’s Executive Director. Credit: UNFPA

Dr. Natalia Kanem, UNFPA’s Executive Director. Credit: UNFPA

By Naureen Hossain
UNITED NATIONS, Sep 26 2024 – On the heels of the Summit of the Future and the sidelines of the United Nations High-Level Meeting Week, governments and philanthropies pledged to commit at least USD 350 million to boost family planning, sexual and reproductive health and supplies on the national and global level. As enshrined in the newly-adopted Pact for the Future, seeking new international finance models is critical to solving the issues that the world faces today. The decision to pledge forward is a demonstration of commitment to ongoing health issues.

On September 24, the United Nations Population Fund (UNFPA), the Bill and Melinda Gates Foundation, Family Planning 2030 (FP2030) and the Children’s Investment Fund Foundation (CIFF) invited prominent figures across the private, development and government sectors to promote political will on the matter of sustainable investments towards sexual and reproductive health (SRH). 

“Investing in reproductive health supplies is a ‘best buy’ for development, empowering women, improving maternal and newborn health outcomes, and uplifting economies,” said Dr. Natalia Kanem, UNFPA’s Executive Director.

When speaking on UNFPA’s partnerships with the co-organizers, Kanem remarked: “What we’re doing is transforming lives. The life of a girl in her community, the life of an adolescent in her city, and empowering communities and families to be able to harness and take control of their futures.”

“So much of our world has been made possible by family planning,” said Dr. Samukeliso Dube, Executive Director of FP2030. “By enabling more women to shape their lives and futures, family planning has helped women to finish their education, join the workforce, ascend to leadership positions, and achieve their dreams.”

Donor countries, such as the United Kingdom, Canada, Norway, and Spain, announced pledges to the UNFPA Supplies Partnership, which delivers modern contraceptives and maternal health supplies to women and girls in low-income countries. Through this partnership, UNFPA has helped to prevent 1.6 million child deaths, 254,000 maternal deaths, and 2.6 million unsafe abortions. The contributions to UNFPA could potentially save up to 9000 women and girls worldwide. As Anneliese Dodds, UK Minister for Development and Women and Inequalities, remarked, investing in SRH was “critical to making sure that women have the power.”

Speakers representing their countries’ governments pledged their support through domestic financial investments. The governments of Madagascar, Nepal, and the Kyrgyz Republic, for example, announced domestic financial commitments that would invest in SRH services in their countries.

Madagascar announced a contribution of USD 15 million to procure health supplies through UNFPA. Their minister of public health, Zely Arivelo Randriamanantany, added that their goal was to increase access to contraceptives by over 50 percent. Arzu Rana Deube, foreign minister of Nepal, announced the government’s commitment of USD 600,000 to purchase high-quality contraceptives. Renat Mavlyanbai Uulu, Advisor to the Minister of Health, of the Kyrgyz Republic, announced a commitment of USD 119,000 to domestic resources for family planning commodities.

Feri Anita Wijayanti, a registered midwife from Indonesia. Credit: UN

Feri Anita Wijayanti, a registered midwife from Indonesia. Credit: UNFPA

As UNFPA Chief of Sexual and Reproductive Health and Rights Ayman Abdelmohsen told IPS, the commitments to domestic financing are significant; it shows that in “allocating from their own resources… and [making] budgetary allocations,”  these governments will prioritize SRH without relying on foreign donors. It is in line with UNFPA’s compact agreements with 44 countries, through which countries will build up their capacity to provide comprehensive reproductive health through their own resources.

Despite the predicted growth in contraceptive access and maternal health by 2030, the current financing gap why this is still far off in the future. The gap currently sits at at least USD 1.5 billion in the world’s poorest countries.

Throughout the event, the speakers emphasized the ‘transformative’ power of SRH in countries. That to invest in SRH is to invest in girls’ and women’s’ agency over the health and life choices. In guaranteeing women’s sexual and reproductive health, it pays forward in protecting families and communities. In terms of financing, every dollar spent on family planning can yield more than 8 dollars in benefits for families and societies.

Investing in healthcare also goes forward to the practitioners within the sector. As Feri Anita Wijayanti, a registered midwife from Indonesia, explained to the panel, many communities rely on the expertise of midwives, whose responsibilities extend “far beyond delivering babies,”  for they are at the frontlines to address other health issues.

“Every second in every corner of the world, midwives work tirelessly to protect the lives of women and babies, and to provide sexual and reproductive health services,” she said. Midwives have the power to save an estimated 4.3 million lives each year by 2025. We urge you to invest in us, to believe in the transformative power of midwives and to begin by investing in sexual and reproductive health.”

The commitments made by countries and the private sector are a step forward in closing the considerable financing gap. They come at a time where senior leadership within the UN, namely the Secretary-General, has called for countries to explore innovative and sustainable financing to address global inequalities. The commitments made at this event demonstrate that despite the challenges to SRH, there is political will in support of, and it can be mobilized to ensure this care for all.

IPSNewsUNBureau
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Dying for a Cause: Environmental Defenders in the Firing Line

In 2017, South African activist Nonhle Mbuthuma took a stand against the powerful oil giant Shell, halting their plans to explore the pristine Wild Coast. Despite facing death threats, she refused to back down. As a co-founder of the Amadiba Crisis Committee and a 2024 Goldman Prize winner, Mbuthuma continues to fight for her community’s […]

MPI Announces Istanbul Türkiye as the Host City for EMEC 2025

Dallas, Texas, Sept. 26, 2024 (GLOBE NEWSWIRE) — Dallas, TX – 26 September, 2024: Meeting Professionals International (MPI), the world’s largest Meetings, Incentives, Conferences and Exhibitions (MICE) association with a global community of 140,000 professionals and membership of 13,000, is excited to announce that its 2025 European Meetings & Events Conference (EMEC) will take place in Istanbul, Türkiye, from 22–25 February, 2025.  

The dynamic city, known for its rich history, culture and unique position bridging Europe and Asia, will once again serve as a vibrant backdrop for the global meetings and events community. The last time EMEC was held in Istanbul was in 2014, and this return marks a significant moment for both MPI and its host. Registration for EMEC Türkiye officially went live on 26 September, 2024, at mpi.org/emec.  

In addition to serving as the largest global MICE association, MPI also boasts the industry’s largest EMEA presence with 1,000 members and 10 Chapters and Clubs. Now in its 37th year, EMEC brings together 300–400 global MICE professionals within a format that has received multiple awards, including recognition by BEA and a Gouden Giraffe. 

Paul Van Deventer, President and CEO of MPI, emphasized the importance of this return to Istanbul, commenting that “EMEC has long been a cornerstone for the global events community, fostering professional development through innovation, learning and connections. Returning to Istanbul after more than a decade is not only a testament to the city’s enduring appeal but also a clear indicator of the excitement and popularity surrounding this iconic destination. Istanbul offers a unique blend of tradition and modernity that resonates with our international audience, and we are thrilled to bring EMEC back to this vibrant city.” 

EMEC is designed with three primary tenets at its core: to serve as an idea incubator for the global MICE community, designed by Europeans for Europeans and to carry a strong reflection of the host destination – its culture, history and heritage. 

İsmail Bütün, General Manager of the Türkiye Tourism Promotion and Development Agency (TGA) echoed Van Deventer’s sentiments, underscoring the impact EMEC will have on their global MICE presence. “Hosting EMEC 2025 is a monumental opportunity for Türkiye to showcase its position on the global MICE stage. Istanbul has a proven track record of hosting large–scale international events, and EMEC’s return highlights our commitment to growing and evolving as a premier destination for meetings and events professionals.” 

As MPI continues to expand the reach of EMEC, the organization is also pleased to announce that it will soon be releasing a request for proposals (RFP) for the 2026 and 2027 host destinations. With the bar set high for EMEC Türkiye in 2025, MPI invites destinations from around EMEA to apply and showcase their ability to host this prestigious conference. 

For more information, visit www.mpi.org/emec.

About MPI 
Meeting Professionals International (MPI) is the largest meeting and event industry association worldwide. The organization provides innovative and relevant education, networking opportunities and business exchanges, and acts as a prominent voice for the promotion and growth of the industry. MPI has a global community of 140,000 engaged meeting and event professionals including nearly 13,000 members. It has It has nearly 70 chapters, clubs and members in more than 75 countries worldwide. “When we meet, we change the world.”  www.mpi.org

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‘We Need Competitive Elections so Only Truly Committed States Are Elected to the UN Human Rights Council’

By CIVICUS
Sep 26 2024 –  
CIVICUS discusses the upcoming election of new members of the United Nations (UN) Human Rights Council with Madeleine Sinclair, New York Office Director and Legal Counsel at the International Service for Human Rights (ISHR).

The Human Rights Council plays a crucial role in addressing global human rights issues and serves as a platform for activists and victims of violations. Its 47 members represent different regional groups. In October, 19 states will stand for 18 seats, with the Asia-Pacific region the only group with more candidates than seats. Many of the candidates have poor human rights records, and one – Saudi Arabia – stands out for its extremely serious rights violations. Civil society calls on UN member states to reject Saudi Arabia’s candidacy and uphold human rights standards when selecting members of the UN’s top human rights body.

Madeleine Sinclair

Why is the election of UN Human Rights Council members important?

As happens every year, the Human Rights Council will soon renew one third of its membership through a secret ballot election. On 9 October, all 193 members of the UN General Assembly will vote for the 18 members who will sit on the UN’s main human rights body from 2025 to 2027.

Elections should provide an opportunity to elect candidates with a strong human rights record. According to the Council’s membership criteria, candidate states should demonstrate a genuine commitment to the promotion and protection of human rights through domestic and international action. They should also demonstrate a willingness to address emerging challenges and crises to ensure the Council’s effectiveness.

How competitive will this year’s election be?

Unfortunately, this election will be nowhere near as competitive as it should be, with only 19 countries standing for 18 seats. These seats are divided among the UN’s five official regional groups, each of which presents its own slate of candidates. But only the Asia-Pacific slate is competitive, with six candidates vying for five seats, while the other four slates are closed, meaning they have as many candidates as seats available. Africa has five candidates for five seats, Latin America and the Caribbean has three for three, Eastern Europe has two for two and Western Europe and Others has two for two.

This election is less competitive than last year’s, when 17 candidates contested 15 seats. Only Latin America and the Caribbean and Eastern Europe had more candidates than seats, resulting in the defeat of Russia. In 2021, all 18 candidates running for 18 seats were elected, receiving between 144 and 189 votes out of a possible 193, despite some having extremely problematic human rights records.

Unfortunately, non-competitive elections are common, with fully closed slates being presented four times since 2008. Other elections have seen only one or two competitive slates. The problem with non-competitive races is they deprive voting states of the opportunity to rigorously evaluate and select candidates based on their records and commitments, potentially compromising the quality of the Council.

But even in closed slates, it’s still possible for unopposed candidates to fail if they don’t receive at least 97 out of 193 votes. In 2023, for example, Burundi and China received the lowest number of votes in their regional groups, sending a message that their candidacies were not fully supported. ISHR encourages voting states to evaluate all candidates carefully and withhold votes from problematic ones, even in closed slates.

Who are the candidates in the October election?

Candidates in this year’s election include Benin, the Democratic Republic of the Congo, Ethiopia, The Gambia and Kenya from the African group. In the Asia and Pacific group, Cyprus, South Korea, the Marshall Islands, Qatar, Saudi Arabia and Thailand are running. Latin America and the Caribbean is represented by Bolivia, Colombia and Mexico. Iceland, Spain and Switzerland are the candidates from Western Europe and Others, while the Czech Republic and North Macedonia are running for Central and Eastern Europe.

This year, one candidate has a particularly poor human rights record: Saudi Arabia. It has closed civic space and has been repeatedly included in the UN Secretary-General’s reprisals report and accused by UN experts of committing war crimes in Yemen. Due to these serious concerns, we are actively campaigning against its election in the Asia and Pacific group.

What’s the role of civil society in this process?

Civil society, including ISHR, has a crucial role to play in advocating for a more effective and accountable Human Rights Council. One of the key areas where reform is needed is closed slates. Competitive elections are essential to ensure that only states with a genuine commitment to human rights are elected.

ISHR has created scorecards to assess and compare the candidates based on their history of cooperation with human rights mechanisms such as the Universal Periodic Review and their engagement with civil society, UN treaty bodies and special procedures. These criteria provide a solid understanding and clear overview of a country’s human rights record and therefore its suitability to sit on the Council. While we understand no country has a perfect record, these criteria aim to provide valuable insights into each state’s commitment to upholding human rights and its potential role on the Council.

In addition to our scorecards, our annual joint pledging event with Amnesty International provides a platform for states to present their candidacies, make strong, public commitments as potential members and receive direct feedback and critical questions from civil society. If all candidates participated in this event, it would increase the political cost of refusing to participate or failing to submit formal pledges and commitments. Such engagement would make it harder for states with poor human rights records to seek a seat without facing scrutiny.

What should be the Council’s priorities?

The Human Rights Council is vital in amplifying the voices of rights holders, victims and human rights defenders, providing them with a platform to expose violations and demand accountability. To fulfil this role effectively, its priorities must focus on being credible, effective and accessible. It should continue to focus on upholding international law universally, supporting the remote and hybrid participation of civil society and ensuring that demands for accountability are promptly addressed.

A credible and effective Council can only function if its members fully cooperate with its mechanisms and adhere to objective human rights criteria. At a time of increasing conflict and crisis, often rooted in repression and human rights violations, the Council’s role in promoting accountability and justice is more important than ever. States should support the work of human rights defenders, whose efforts to prevent violations, document abuses and provide essential services are essential to crisis resolution.

To address these conflicts, states must apply human rights standards consistently. Selective or inconsistent application of standards undermines the international framework and the credibility of those involved. International human rights law, when applied consistently and in a principled manner, remains the best guide to achieving a more just, peaceful and inclusive world.

Get in touch with ISHR through its website or Facebook page, and follow @ishrglobal on Instagram and @ISHRglobal and @Madeleine_ISHR on Twitter.

 


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